Chargaff’s rule

1905-2002

By Erwin chargaff

It states that in all DNA, Pyrimidines and Purines must have 1:1

Adenine : Thymine

Cytosine : Guanine

i.e., the amount of adenine = amount of thymine

similarly, the amount of cytosine = amount of guanine.

It indicated that DNA is symmetrical.                (A)Double bond (T)    and   (C) triple bond (G)