Immune deficiency

Immune deficiency is a condition in which the system fails to protect the host from disease causing agent or from malignant cells.

Immune deficiency or immune deficiency is a state in which the immune systems ablity to fight infectious disease is compromised or entirely absent.

Two types of immune deficiency

  • Primary/congenital/inherited immunodeficiency:- It results from genetic or development defect

Parents ——–:- disease causing genes —–:-child born with IgA deficiency, CVI, SCID, or other primary immunodeficiency.

  • Secondary/acquired immunodeficiency:- It results from loss of immune function due to exposure of various agents

Intravenous (IV) drug abuse (injection), unsafe sexual activity and other risk behaviours, malnutrition, chromic diseases (such as diabetes), medications (corticosteroids) ——–:-  development of AIDS or other secondary immunodeficiency ——:- impaired/ weakened immune response.

It can be specific or non specific.

  • Specific:– abnormalities of B and T cells
  • Non-specific:- abnormalities of non specific components